Depakote Sprinkle Capsules Color
The Depakote Sprinkle Capsules (125 mg) are white opaque and blue. 1
Product Description
According to the FDA drug label, Depakote Sprinkle Capsules contain specially coated particles of divalproex sodium equivalent to 125 mg of valproic acid in a hard gelatin capsule. The capsule itself has a distinctive two-tone appearance with white opaque and blue coloring 1.
Inactive Ingredients Contributing to Color
The blue coloring comes from FD&C Blue No. 1, while the capsule also contains D&C Red No. 28 among its inactive ingredients. Additional components include cellulosic polymers, gelatin, iron oxide, magnesium stearate, silica gel, titanium dioxide, and triethyl citrate 1.
Packaging Information
These white and blue capsules are supplied in:
- Bottles of 100 (NDC 0074-6114-13)
- Unit Dose Packages of 100 (NDC 0074-6114-11)
Storage should be below 77°F (25°C) 1.
Clinical Context
The Sprinkle formulation was specifically designed for patients who have difficulty swallowing tablets. The capsule can be pulled apart and the coated particles sprinkled on food, making administration easier while maintaining the delayed-release properties of the medication 2. This formulation demonstrates high patient and parent acceptance, with studies showing preference due to ease of administration and improved palatability 3.