Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 5, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Movable Mass in the Right Upper Quadrant

  • Single most likely diagnosis
    • Gallbladder pathology (e.g., gallstones, cholecystitis): The right upper quadrant is a common location for gallbladder issues, and a movable mass could indicate an inflamed or distended gallbladder.
  • Other Likely diagnoses
    • Hepatic cyst or tumor: A mass in the liver could be palpable and movable, depending on its size and location.
    • Right kidney pathology (e.g., hydronephrosis, renal cyst): Although the kidneys are typically located more posteriorly, a significantly enlarged right kidney could present as a movable mass in the right upper quadrant.
    • Intestinal obstruction or volvulus: Although less common, a movable mass could be related to an intestinal issue, such as an obstruction or volvulus, especially if it involves the small intestine or the hepatic flexure of the colon.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Aortic aneurysm (although typically more central and not usually movable): An aortic aneurysm can present with a palpable mass, and missing this diagnosis could be catastrophic.
    • Liver abscess: A liver abscess can cause a palpable mass and is a serious condition that requires prompt treatment.
    • Perforated viscus (e.g., perforated ulcer, perforated appendix): A perforated viscus can lead to peritonitis and sepsis, making it a critical diagnosis not to miss.
  • Rare diagnoses
    • Right adrenal gland pathology (e.g., adrenal tumor, pheochromocytoma): Although rare, adrenal gland issues can present with a palpable mass in the right upper quadrant.
    • Retroperitoneal tumor (e.g., sarcoma, lymphoma): Tumors in the retroperitoneal space can grow large enough to be palpable and could be mistaken for a movable mass in the right upper quadrant.
    • Diaphragmatic hernia: A diaphragmatic hernia can allow abdominal contents to herniate into the thoracic cavity, potentially presenting as a movable mass in the right upper quadrant.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.