Can Raynaud's (Raynaud's phenomenon) cause false low blood sugar readings?

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Last updated: June 5, 2025View editorial policy

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From the Research

Raynaud's phenomenon can potentially cause false low blood sugar readings when using glucometers that require a finger prick, as evidenced by a study published in 2022 1 that discussed artifactual hypoglycemia in a patient with systemic sclerosis, which is often associated with Raynaud's phenomenon. This occurs because Raynaud's causes blood vessels in the extremities to narrow excessively in response to cold or stress, limiting blood supply to the fingertips where testing typically occurs. Some key points to consider:

  • During a Raynaud's episode, reduced blood flow to the fingers can lead to inadequate blood samples and artificially low glucose readings.
  • The pathophysiology of Raynaud's phenomenon involves a complex interplay of neural and vascular mechanisms, including the release of vasoconstrictors such as endothelin-1 and angiotensin, as well as impaired vasodilation 2.
  • If you have Raynaud's and need to check your blood sugar, warming your hands first by running them under warm water, rubbing them together, or using hand warmers may help improve blood flow and accuracy of glucose readings.
  • Alternatively, consider testing at an alternate site like the forearm if your glucometer allows this option.
  • You might also discuss with your healthcare provider about continuous glucose monitoring systems that don't rely on fingerstick samples, which have been shown to be clinically valuable in reducing risks of hypoglycemia and hyperglycemia, as well as improving patient quality of life 3. Understanding this interaction is important because inaccurate low readings could lead to unnecessary treatment for hypoglycemia or inappropriate diabetes management decisions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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