From the FDA Drug Label
Directions for itching of skin irritation, inflammation, and rashes: adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily children under 2 years of age: ask a doctor children under 12 years of age: ask a doctor
Prilla (hydrocortisone) cream can be used in children 2 years of age and older. However, for children under 2 years of age and children under 12 years of age, it is recommended to ask a doctor before use 1.
From the Research
Prilla (hydrocortisone) cream can be used in children, but with caution and appropriate dosing. For children over 2 years of age, hydrocortisone cream is generally considered safe when used as directed for short periods (typically 1-2 weeks) on small areas of skin, as suggested by the most recent and relevant study on the safety of topical medications in pediatric populations 2.
Key Considerations
- For infants and children under 2, it should only be used under direct medical supervision.
- When applying, use the minimum effective amount, applying a thin layer to affected areas 1-2 times daily.
- Avoid using on large body surface areas, under occlusive dressings, or for extended periods in children, as this increases systemic absorption.
- Parents should discontinue use and consult a healthcare provider if the condition worsens or shows no improvement after 7 days.
Mechanism and Precautions
Hydrocortisone works by reducing inflammation, redness, and itching by suppressing the immune response in the skin. Children may absorb proportionally more medication through their skin than adults due to their higher surface area-to-weight ratio, which is why cautious use is important, as noted in various studies on pediatric dermatology 2, 3.
Additional Guidance
While other studies discuss the use of antihistamines 4, retinoids 5, 6, and contact dermatitis to medications and skin products 3, the primary concern with hydrocortisone cream in children revolves around its safe application and potential for systemic absorption, making cautious use under medical guidance paramount for minimizing risks and ensuring the best outcomes in terms of morbidity, mortality, and quality of life.