Is retinal detachment a side effect of the COVID-19 (Coronavirus Disease 2019) vaccine?

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Last updated: June 5, 2025View editorial policy

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From the Guidelines

Retinal detachment is not a recognized side effect of COVID-19 vaccines, as extensive safety monitoring has not established a causal link between vaccination and this condition. The provided evidence does not support a direct association between COVID-19 vaccination and retinal detachment 1. The study discusses various eye conditions, including those related to travel and COVID-19 infection, but does not mention retinal detachment as a side effect of the vaccine.

Key points to consider:

  • Retinal detachment is a serious eye condition that typically occurs due to aging, eye trauma, previous eye surgery, severe nearsightedness, or family history of the condition.
  • COVID-19 infection has been linked to various ocular conditions, including retinal vein or artery occlusion, ischemic optic neuropathy, and other inflammatory conditions 1.
  • However, these conditions are associated with the infection itself, not the vaccine.
  • If symptoms of retinal detachment occur, such as sudden flashes of light, floaters, or a curtain-like shadow over vision, immediate medical attention is essential to prevent permanent vision loss, regardless of vaccination status.

From the Research

Retinal Detachment and COVID-19 Vaccine

  • Retinal detachment is a rare but serious condition that can cause permanent vision loss if left untreated 2.
  • There have been reports of retinal detachment occurring after COVID-19 vaccination, although the exact relationship between the two is still being studied 2, 3, 4.
  • A case study published in 2021 reported a rare instance of bilateral retinal detachments in a healthy 22-year-old woman after receiving the Moderna COVID-19 vaccine 2.
  • Another study published in 2021 found that the COVID-19 pandemic had an impact on the characteristics of retinal detachments, with a higher percentage of patients presenting with macular detachment during the pandemic period 5.
  • A review of challenges and solutions for retinal detachment during the COVID-19 era highlighted the importance of timely diagnosis and treatment, as well as the potential benefits of telemedicine and optimized guidelines for RD management 6.
  • A narrative literature review published in 2022 found that COVID-19 vaccine-associated ocular adverse events, including retinal conditions, are rare and that the benefits of vaccination outweigh the risks 3.
  • A retrospective cohort study published in 2023 found a higher risk of retinal vascular occlusion after COVID-19 vaccination, particularly in the first 2 weeks after vaccination 4.

Key Findings

  • Retinal detachment is a potential complication of COVID-19 vaccination, although the exact risk is still being studied 2, 4.
  • The COVID-19 pandemic has had an impact on the characteristics and management of retinal detachments 5, 6.
  • Timely diagnosis and treatment of retinal detachment are crucial to prevent permanent vision loss 2, 6.
  • COVID-19 vaccine-associated ocular adverse events are rare, and the benefits of vaccination outweigh the risks 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

COVID-19 Vaccination and The Eye.

American journal of ophthalmology, 2022

Research

Impact of the COVID-19 pandemic on characteristics of retinal detachments: the Canadian experience.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2021

Research

Retinal detachment during COVID-19 era: a review of challenges and solutions.

Spektrum der Augenheilkunde : Zeitschrift der Osterreichischen Ophthalmologischen Gesellschaft, OOG, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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