From the FDA Drug Label
Vertigo The FDA drug label lists vertigo as one of the adverse reactions reported with prednisone.
- Vertigo is mentioned under the subsection of adverse reactions in the Nervous System category.
- The presence of vertigo in the list indicates that prednisone can cause vertigo in some patients. 1
From the Research
Prednisone can cause vertigo as a side effect, although the provided evidence does not directly support this claim, and the relationship between prednisone and vertigo is more complex, as prednisone is sometimes used to treat vertigo in certain conditions, such as Ménière's disease, as shown in the study by 2. The mechanism behind prednisone-induced vertigo, if it occurs, likely relates to the medication's effects on fluid balance, electrolyte levels, and possibly its impact on the inner ear or central nervous system. If you experience vertigo while taking prednisone, you should not abruptly stop the medication, as this can be dangerous. Instead, contact your healthcare provider promptly to discuss your symptoms. They may adjust your dosage, recommend a slower tapering schedule, or suggest supportive measures to manage the vertigo. Other medications might be considered if the vertigo is severe or significantly impacts your daily activities. Staying well-hydrated and avoiding sudden head movements may help minimize vertigo symptoms while on prednisone therapy. Some studies, such as 3, 4, and 5, discuss vestibular rehabilitation therapy as a treatment option for vertigo, but they do not specifically address the relationship between prednisone and vertigo. However, the study by 2 suggests that prednisone can be used to control refractory vertigo in Ménière's disease, highlighting the complex relationship between prednisone and vertigo. Additionally, the study by 6 provides a practical approach to diagnosing the cause of vertigo, which can be helpful in determining the best course of treatment. It is essential to consult with a healthcare provider to determine the best approach for managing vertigo symptoms while taking prednisone. Some key points to consider when managing vertigo include:
- Maintaining balance requires sensory inputs from the vestibular, visual, and somatosensory systems
- Causes of vertigo are most commonly otological, followed by central, somatosensory, and visual
- The tempo of the vertiginous attacks and other associated symptoms can help differentiate the other causes of peripheral vertigo
- Vestibular rehabilitation therapy can be an effective treatment option for vertigo, as shown in the studies by 3, 4, and 5.