Key Information
Lubiprostone (Amitiza) is a chloride channel activator available as oral capsules in two strengths:
- 8 mcg capsules (pink) - approved for IBS-C in women ≥18 years
- 24 mcg capsules (orange) - approved for chronic idiopathic constipation (CIC) and opioid-induced constipation (OIC) in adults 1
The medication was initially approved by the FDA in 2006 and has been available in various markets since then 1, 2.