From the Guidelines
Dexedrine (dextroamphetamine) should be started at a dose of 2.5 mg, generally given in the morning after breakfast and around noon after lunch, with careful documentation of prior treatments and regular monitoring of side effects 1. The recommended dosing for Dexedrine (dextroamphetamine) is based on the practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults, which suggests starting with a low dose and gradually increasing as needed 1.
- Key considerations for dosing include:
- Starting dose: 2.5 mg for DEX/AMP, given in the morning and around noon
- Minimum effective dose: 2.5 mg of AMP in children and adolescents
- Maximum dose: not explicitly stated in the provided evidence, but should be determined based on individual patient response and side effects
- Important aspects of Dexedrine treatment include:
- Regular monitoring of vital signs, including blood pressure and pulse, especially in adults who should have these checked quarterly 1
- Assessment of treatment response and management of side effects, such as increased heart rate, blood pressure, decreased appetite, and insomnia
- Awareness of the potential for dependence and the need for regular monitoring by a healthcare provider 1
From the Research
Dexedrine Dosing
The recommended dosing for Dexedrine (dextroamphetamine) is not explicitly stated in the provided studies. However, some general information about the medication and its use in treating Attention Deficit Hyperactivity Disorder (ADHD) can be found:
- Dexedrine is a type of stimulant medication, which is commonly used to treat ADHD 2, 3, 4, 5.
- The medication works by releasing dopamine and norepinephrine in the central nervous system, helping to improve focus and reduce impulsivity and hyperactivity 2.
- While the exact dosing for Dexedrine is not specified, other studies suggest that stimulant medications like methylphenidate and lisdexamfetamine are typically recommended as first-line treatments for ADHD, with dosing varying depending on the specific formulation and patient response 3, 4.
- It's worth noting that the use of stimulant medications like Dexedrine can be associated with side effects, including loss of appetite, sleep problems, and mood disturbances 6.
- Cardiovascular effects of stimulant medications, including Dexedrine, have also been studied, with findings suggesting that these medications can cause minor increases in blood pressure and heart rate, but the risk of sudden death is extremely rare 5.