From the FDA Drug Label
For best results, apply 1 mL with applicator 2 times a day directly onto the scalp in the hair loss area. Using more or using more often will not improve results. Apply minoxidil topical solution 5% once in the morning and once at night. The nighttime application should occur 2 to 4 hours before going to bed to allow for drying.
The recommended dosing of minoxidil for the treatment of androgenetic alopecia is 1 mL, twice a day, directly onto the scalp in the hair loss area. It is essential to use the applicator to apply the correct amount and avoid using more than the recommended dose, as this will not improve results and may increase the risk of side effects 1.
From the Research
For the treatment of androgenetic alopecia, minoxidil is typically recommended as a 5% solution for men and a 2% solution for women, applied twice daily to the affected areas of the scalp, as supported by the most recent and highest quality study 2. Men can use either concentration, but the 5% solution has shown greater efficacy. Each application should use approximately 1 mL of solution, ensuring the total daily dose does not exceed 2 mL. The solution should be applied to a dry scalp and allowed to dry completely before using styling products or going to bed. Some key points to consider when using minoxidil for androgenetic alopecia include:
- Patients should continue treatment indefinitely to maintain results, as hair loss typically resumes within 3-4 months of discontinuation 3.
- Minoxidil works by prolonging the growth phase of hair follicles and increasing follicular size through vasodilation and potassium channel opening, which improves blood flow to the hair follicles 4.
- Initial shedding may occur in the first few weeks of treatment, which is normal and indicates the medication is working 5.
- Visible results typically take 4-6 months of consistent use to appear 6. It's also important to note that minoxidil can be used in combination with other treatments, such as spironolactone, to enhance its efficacy 2, 6. However, the choice of treatment should be individualized based on the patient's specific needs and medical history.