What is the rash in infants caused by increased oil in the skin, also known as seborrhoeic dermatitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 6, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Cradle cap, also known as seborrhoeic dermatitis, is the rash infants get due to increased oil in the skin. This condition is characterized by yellowish, greasy, scaly patches on the scalp and sometimes other areas like the face, ears, and diaper area. It occurs when the oil-producing sebaceous glands in a baby's skin become overactive, leading to an accumulation of skin cells that don't shed normally. To treat cradle cap, gently wash your baby's scalp daily with a mild baby shampoo, then use a soft brush to loosen the scales. For more persistent cases, applying a small amount of mineral oil, petroleum jelly, or baby oil to the scalp about 15 minutes before shampooing can help soften the scales. If these home remedies don't work, your pediatrician might recommend a medicated shampoo containing 2% ketoconazole, low-strength hydrocortisone cream (0.5-1%), or selenium sulfide 1. Some studies have also explored the use of topical coal tar in the treatment of seborrheic dermatitis, although its use in infants is not well-studied 1. Cradle cap typically resolves on its own within a few weeks or months as the baby's sebaceous glands mature and reduce oil production, though it may occasionally recur until the child reaches toddlerhood. Key considerations for treatment include:

  • Gentle skin care to avoid irritating the skin
  • Avoiding harsh shampoos or soaps
  • Using soft brushes to loosen scales
  • Applying topical treatments as recommended by a pediatrician It's essential to differentiate cradle cap from other skin conditions, such as atopic dermatitis, which may require different treatment approaches 1.

From the FDA Drug Label

Seborrheic dermatitis: Ketoconazole Cream 2% should be applied to the affected area twice daily for four weeks or until clinical clearing. The rash in infants caused by increased oil in the skin is seborrhoeic dermatitis.

  • It is also known as seborrheic dermatitis.
  • The treatment for seborrheic dermatitis using Ketoconazole Cream 2% is applied twice daily for four weeks or until clinical clearing 2.

From the Research

Seborrhoeic Dermatitis in Infants

The rash in infants caused by increased oil in the skin is known as seborrhoeic dermatitis. This condition is characterized by:

  • Yellowish, scaly patches on the scalp, also known as "cradle cap" 3
  • Little or no itching 4
  • Typical skin symptoms, distribution, and evolution 4

Causes and Triggers

The exact cause of seborrhoeic dermatitis in infants is still debated, but it is thought to be related to:

  • Excessive sebaceous gland activity from maternal hormones 3
  • Cutaneous microbiome alterations 3
  • Fungal colonization by Malassezia spp. 3, 5
  • Candida albicans may also play a role in the pathogenesis of infantile seborrhoeic dermatitis 4

Treatment and Management

Treatment for seborrhoeic dermatitis in infants typically involves:

  • Shampooing and removing scales with a soft brush after applying mineral oil or petrolatum 6
  • Topical antifungal agents, such as ketoconazole cream 5, 7
  • Topical corticosteroids, such as hydrocortisone cream 7
  • Baby shampoos enriched with emollient agents and vegetable oils may also be effective in managing "cradle cap" 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

An Overview of the Diagnosis and Management of Seborrheic Dermatitis.

Clinical, cosmetic and investigational dermatology, 2022

Research

[Infantile seborrheic dermatitis and related syndromes. Diagnostic and pathogenetic problems].

La Pediatria medica e chirurgica : Medical and surgical pediatrics, 1987

Research

Role of antifungal agents in the treatment of seborrheic dermatitis.

American journal of clinical dermatology, 2004

Research

Comparative study of 2% ketoconazole cream and 1% hydrocortisone cream in the treatment of infantile seborrheic dermatitis.

Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.