Does Lyme disease contraindicate pacemaker (permanent artificial cardiac pacemaker) extraction?

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Last updated: February 24, 2025 • View editorial policy

From the Guidelines

Lyme disease does not contraindicate pacemaker extraction, but it requires careful consideration and management to minimize complications. The decision to proceed with pacemaker extraction in a patient with Lyme disease should be made on a case-by-case basis, weighing the risks and benefits for each individual patient 1.

Key Considerations

  • Patients with active Lyme disease should be treated with appropriate antibiotics before the extraction if possible, with the standard treatment for early Lyme disease being doxycycline 100 mg twice daily for 10-14 days, and intravenous ceftriaxone 2 g daily for 14-28 days for late or complicated Lyme disease 2, 1.
  • The pacemaker extraction should ideally be delayed until the infection is adequately treated to reduce the risk of complications.
  • Special attention should be given to potential Lyme carditis, which may affect heart rhythm during and after the procedure.
  • The medical team should be prepared for possible complications and may need to adjust their approach based on the patient's specific condition.

Management Approach

  • Temporary pacing modalities are recommended rather than implanting a permanent pacemaker for patients with symptomatic bradycardia due to Lyme carditis that cannot be managed medically, based on a strong recommendation with moderate-quality evidence 2, 1.
  • Post-procedure, careful monitoring for signs of infection or cardiac complications is crucial.
  • The patient's condition and response to treatment should guide the management approach, with a focus on minimizing morbidity, mortality, and improving quality of life.

From the Research

Lyme Disease and Pacemaker Extraction

  • Lyme disease does not necessarily contraindicate pacemaker extraction, as evidenced by a case report of successful permanent pacemaker explantation after diagnosis and treatment of Lyme carditis complete heart block 3.
  • The decision to extract a pacemaker in a patient with Lyme disease should be made on a case-by-case basis, considering the individual's specific condition and the potential for spontaneous resolution of cardiac conduction abnormalities 3, 4.
  • In patients with Lyme carditis, the use of a temporary pacemaker may be necessary, but permanent pacemaker implantation is often contraindicated due to the frequent transient nature of the condition 4.
  • The incidence of permanent pacemaker implantation in patients hospitalized with Lyme disease is relatively low, around 1% of all Lyme hospitalizations and 11% of patients with Lyme carditis-associated conduction system disease 5.

Predictors of Pacemaker Implantation

  • Predictors of permanent pacemaker implantation in patients with Lyme disease include older age, complete heart block, and sinoatrial node dysfunction 5.
  • The presence of cardiac conduction system disease, such as complete heart block, is a significant predictor of permanent pacemaker implantation in patients with Lyme carditis 5.

Considerations for Pacemaker Extraction

  • Before extracting a pacemaker in a patient with Lyme disease, it is essential to ensure that the patient's cardiac conduction abnormalities have resolved and that there is no ongoing need for pacing 3.
  • The use of scoring systems, such as the Suspicious Index in Lyme Carditis (SILC) score, may help identify patients at low risk for Lyme carditis and prevent unnecessary pacemaker implantation 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.