Yes, the flu shot can be administered in the thigh
For infants and young children, the anterolateral thigh is the preferred and recommended site for intramuscular influenza vaccination. 1, 2
Site Selection by Age
The choice of injection site for influenza vaccine depends on the patient's age:
Infants and Young Children
- The anterolateral aspect of the thigh is the preferred site for infants and younger children 1, 2, 3
- This applies to children who lack adequate deltoid muscle mass
- Recommended needle length: 7/8 to 1 inch for children aged <12 months for intramuscular vaccination into the anterolateral thigh 4, 5
Older Children and Adults
- The deltoid muscle is the preferred site for adults and older children with adequate deltoid muscle mass 1, 2
- When injecting into the deltoid muscle among children with adequate deltoid muscle mass, a needle length of 7/8 to 1.25 inches is recommended 4, 5
Key Clinical Considerations
All intramuscular influenza vaccines should be administered by needle and syringe only (with one specific exception: Afluria multidose vial can alternatively be given by PharmaJet Stratis jet injector for persons aged 18-64 years only) 2
The thigh site is not merely acceptable but is actually the recommended anatomical location for the pediatric population, particularly those under 3 years of age. This recommendation has remained consistent across multiple ACIP guidelines from 2003 through 2025 1, 2, 4, 5, 3, 6, 7.
Common Pitfall to Avoid
Do not attempt to use the deltoid muscle in infants or young children who lack adequate muscle mass in that area. The anterolateral thigh provides better muscle mass and is the safer, more effective site for this age group.