MDI with Spacer Smart Phrase
Use a valved holding chamber (spacer) with your MDI by actuating once into the spacer, then taking a slow, deep breath over 3-5 seconds followed by a 10-second breath hold—this technique is as effective as nebulizer therapy for mild-to-moderate exacerbations and dramatically improves drug delivery to the lungs. 1
Proper Technique (Step-by-Step)
For Adults and Children ≥4 Years Old:
- Shake the MDI before each use 2
- Actuate only once into the spacer per inhalation 1
- Immediately inhale after actuation—delays reduce available dose 3
- Take a slow, deep breath (30 L/min or 3-5 seconds duration) 1
- Hold breath for 10 seconds after inhalation 1
- Wait between puffs if multiple doses prescribed
- Rinse mouth and spit after inhaled corticosteroids to reduce thrush risk 1
For Children <4 Years Old (Face Mask):
- Ensure tight seal with face mask 1
- Allow 3-5 inhalations per actuation 1
- Note: Face mask reduces lung delivery by 50% compared to mouthpiece 1
Dosing Examples for Acute Exacerbations
Adults: 4-8 puffs albuterol (90 mcg/puff) every 20 minutes for 3 doses, then every 1-4 hours as needed 2
Children: 4-8 puffs every 20 minutes for 3 doses, then every 1-4 hours as needed 2
Alternative (severe cases): Up to 20 actuations may be used in acute severe asthma 4
Spacer Maintenance
Clean plastic spacers monthly by rinsing with dilute household dishwashing detergent (1:5000 dilution or drops per cup of water) and let drip dry—this reduces static charge and enhances drug delivery 1
Key Clinical Points
- MDI plus spacer equals nebulizer efficacy in mild-to-moderate exacerbations with proper technique and coaching 2, 1
- Spacers reduce oropharyngeal deposition by 50-80%, decreasing systemic absorption and local side effects like thrush 1
- Coordination is less critical with spacers compared to MDI alone, making them ideal for young children, elderly, and those with poor technique 1
- Video instruction significantly improves technique in children and should be repeated over time 5
Common Pitfalls to Avoid
- Not shaking the MDI before use (most common error—only 16-18% do this correctly) 6
- Actuating multiple times into spacer before inhalation—actuate once per breath only 1
- Delaying inhalation after actuation—dose declines rapidly with delays 3
- Insufficient breath holding—10 seconds is essential for optimal deposition 6
- Breathing too fast—slow inhalation (3-5 seconds) is critical 1