No, Wegovy does not have a 7.5 mg dose
Wegovy (semaglutide) is available in the following FDA-approved doses: 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg for subcutaneous injection once weekly 1. There is no 7.5 mg formulation of Wegovy.
Available Wegovy Dosing
According to the FDA drug label, Wegovy comes in two pen configurations 1:
- 0.5 mL single-dose pens containing 0.25 mg, 0.5 mg, or 1 mg of semaglutide
- 0.75 mL single-dose pens containing 1.7 mg or 2.4 mg of semaglutide
Standard Dosing Schedule
The approved maintenance dose is 2.4 mg once weekly, reached through gradual titration 2:
- Start at 0.25 mg weekly for 4 weeks
- Increase to 0.5 mg weekly for 4 weeks
- Increase to 1.0 mg weekly for 4 weeks
- Increase to 1.7 mg weekly for 4 weeks
- Reach maintenance dose of 2.4 mg weekly after 16 weeks
Higher Dose Under Investigation
A 7.2 mg dose (not 7.5 mg) is currently being studied in clinical trials but is not yet FDA-approved 3, 4. The STEP UP trials demonstrated that semaglutide 7.2 mg produced greater weight loss than 2.4 mg (-18.7% vs -15.6% body weight at 72 weeks) in adults with obesity 3. However, this higher dose showed increased gastrointestinal adverse events and dysaesthesia compared to the 2.4 mg dose.
Key Clinical Caveat
Some patients may confuse the 1.7 mg dose with "7" or misunderstand dosing instructions. The 1.7 mg dose is a legitimate FDA-approved step in the titration schedule and can serve as a maintenance dose for adolescents ≥12 years 5 or adults who achieve adequate response at this submaximal dose 2.