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Differential Diagnosis for a Raised Circular Nodule

Single Most Likely Diagnosis

  • Dermatofibroma: A common, benign skin growth that often appears as a firm, raised nodule, typically following minor injury, which matches the description given.

Other Likely Diagnoses

  • Molluscum Contagiosum: A viral skin infection causing small, pearly, or flesh-colored bumps, which can sometimes appear as firm, raised nodules.
  • Keratoacanthoma: A low-grade, or sometimes considered benign, skin tumor that can present as a firm, round nodule, often with a central crater.
  • Seborrheic Keratosis: A benign skin growth that can appear as a firm, raised nodule, although they are more often pigmented and have a stuck-on appearance.

Do Not Miss Diagnoses

  • Basal Cell Carcinoma: The most common form of skin cancer, which can initially present as a small, firm, raised nodule. Early detection is crucial for effective treatment.
  • Squamous Cell Carcinoma: Another form of skin cancer that can appear as a firm nodule, often in sun-exposed areas. It has a higher potential for metastasis than basal cell carcinoma.
  • Melanoma: The most dangerous form of skin cancer, which can present as a new or changing mole. Although less common, it's critical to consider due to its high mortality rate if not caught early.

Rare Diagnoses

  • Metastatic Skin Nodule: Rarely, cancers from other parts of the body can metastasize to the skin, presenting as firm nodules.
  • Leukemia Cutis: Involvement of the skin by leukemia cells, which can cause firm nodules among other skin manifestations.
  • Sarcoidosis: A condition that can cause small, firm nodules on the skin, among other systemic symptoms, due to the formation of granulomas in various organs.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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