What is the recommended duration of antibiotic therapy for volvulus?

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From the Research

Volvulus antibiyoterapisi süresi genellikle 3-7 gün olmalıdır, bu süre klinisyenin değerlendirmesine bağlı olarak değişebilir. Volvulus tedavisinde antibiyotik seçimi ve süresi hastalığın şiddeti, komplikasyonların varlığı ve cerrahi müdahaleye gerek olup olmadığı gibi faktörlere bağlı olarak değişebilir.

  • Basit volvulus vakalarında, özellikle bağırsak iskemisi veya perforasyon olmadan başarılı bir şekilde reduksiyona ulaşıldığında, 3-5 gün süreyle geniş spektrum antibiyotik kullanımı genellikle yeterlidir.
  • Bağırsak iskemisi, perforasyon veya peritonit şüphesi veya teyidi olan vakalarda ise 5-7 gün süreyle antibiyotik tedavisi önerilir.
  • Sık kullanılan antibiyotik rejimlerine gram-negatif ve anaerob bakterileri kapsayan kombinasyonlar dahildir, örneğin:
    • Ceftriaxone (1-2g IV her 24 saatte) + Metronidazol (500mg IV her 8 saatte)
    • Piperacillin-tazobactam (3.375g IV her 6 saatte)
  • Kültür sonuçları mevcut olduğunda antibiyotik tedavisi buna göre ayarlanmalıdır.
  • Volvulus tedavisinde antibiyotiklerin amacı, özellikle bağırsak duvarı iskemisi olduğunda, bakteriyel translokasyondan kaynaklanan enfeksiyonları önlemek veya tedavi etmektir.
  • Antibiyotik tedavisi, birçok volvulus vakasının endoskopik veya cerrahi müdahale gerektirdiği için acil cerrahi konsültasyon dahil kapsamlı bir yönetim yaklaşımının bir parçasıdır 1, 2.

References

Research

Volvulus of the gastrointestinal tract.

British journal of hospital medicine (London, England : 2005), 2024

Research

Broad-spectrum antimicrobials and the treatment of serious bacterial infections: getting it right up front.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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