What is the triangle of death and its associated structures and complications?

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Last updated: June 7, 2025View editorial policy

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From the Guidelines

The triangle of death, also known as the lethal triad, refers to a state of profound acidosis, hypothermia, and coagulopathy that occurs in severely injured patients with continuing bleeding or deep haemorrhagic shock. This condition is dangerous because it can lead to a high risk of morbidity and mortality if not promptly addressed. The triangle of death is characterized by the following components:

  • Acidosis: a state of increased acidity in the blood, which can lead to organ dysfunction and failure
  • Hypothermia: a state of decreased body temperature, which can lead to coagulopathy and increased bleeding
  • Coagulopathy: a state of impaired blood clotting, which can lead to uncontrolled bleeding and hemorrhage

The following table explains the triangle of death and its associated structures and complications:

Component Description Complications
Acidosis Increased acidity in the blood Organ dysfunction and failure
Hypothermia Decreased body temperature Coagulopathy and increased bleeding
Coagulopathy Impaired blood clotting Uncontrolled bleeding and hemorrhage

According to the European guideline on management of major bleeding and coagulopathy following trauma: sixth edition 1, the triangle of death is a critical condition that requires prompt recognition and treatment to prevent morbidity and mortality. The guideline recommends early control of bleeding, proper resuscitation, and blood transfusion to achieve optimal outcomes. Additionally, the concept of damage control, which consists of abbreviated resuscitative laparotomy, intensive care treatment, and definitive surgical repair, has been shown to be beneficial in reducing morbidity and mortality in severely injured patients 1.

In summary, the triangle of death is a critical condition that requires prompt recognition and treatment to prevent morbidity and mortality, and the concept of damage control has been shown to be beneficial in reducing morbidity and mortality in severely injured patients. Key points to consider in the management of the triangle of death include:

  • Early control of bleeding and proper resuscitation
  • Blood transfusion and coagulopathy management
  • Damage control techniques, including abbreviated resuscitative laparotomy and intensive care treatment
  • Definitive surgical repair when target parameters have been achieved.

From the Research

Definition of the Triangle of Death

The triangle of death refers to a region in the groin area where the femoral vein, artery, and nerve are located, and is associated with a high risk of severe bleeding and complications in cases of trauma or injury [ 2 ].

Associated Structures

The triangle of death is bounded by the following structures:

  • The inguinal ligament
  • The lacunar ligament
  • The femoral vein and artery

Complications

Complications associated with the triangle of death include:

  • Severe bleeding and hemorrhage
  • Injury to the femoral vein, artery, or nerve
  • Infection and sepsis
  • Amputation and fractures [ 2 ]

Table Explaining the Triangle of Death

Structure Location Complications
Femoral Vein Medial aspect of the femoral sheath Severe bleeding, hemorrhage
Femoral Artery Lateral aspect of the femoral sheath Severe bleeding, hemorrhage
Femoral Nerve Posterior aspect of the femoral sheath Nerve damage, numbness
Inguinal Ligament Bounding the triangle of death Injury, bleeding
Lacunar Ligament Bounding the triangle of death Injury, bleeding

Management of Complications

Management of complications associated with the triangle of death requires a multidisciplinary approach, including:

  • Damage control resuscitation
  • Emergency vascular interventions
  • Targeted temperature management for brain protection [ 2 ]
  • Surgical repair of injured structures [ 3, 4 ]

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Inguinal anatomy.

Journal of anatomy, 1979

Research

Femoral artery exposure for endovascular aneurysm repair through oblique incisions.

Journal of endovascular surgery : the official journal of the International Society for Endovascular Surgery, 1998

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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