From the Research
Dry lips can be caused by deficiencies in several vitamins, particularly B vitamins and vitamin A, with riboflavin (vitamin B2) being a key contributor, as evidenced by a study published in 2014 1. The most common vitamin deficiencies linked to dry lips include:
- Vitamin B2 (riboflavin)
- Vitamin B3 (niacin)
- Vitamin B6 (pyridoxine)
- Vitamin B12 (cobalamin)
- Vitamin A Riboflavin deficiency often manifests as cracked corners of the mouth (angular cheilitis) and dry, chapped lips, as supported by a study from 2000 2. Niacin deficiency can cause inflammation and dryness of the lips and mouth. Vitamin B6 and B12 deficiencies may lead to general mucosal dryness including the lips. Vitamin A deficiency can cause keratinization of mucous membranes, resulting in dry, scaly lips. To address these deficiencies, a daily B-complex supplement containing 25-100 mg of most B vitamins and 1-3 mcg of B12, along with 700-900 mcg of vitamin A (as retinol or beta-carotene) is typically recommended, based on the findings of a 2024 study 3. These vitamins help maintain healthy epithelial tissues and mucous membranes throughout the body. While supplements can help, incorporating foods rich in these vitamins—such as dairy, eggs, leafy greens, nuts, and orange/yellow vegetables—can address the underlying deficiencies more naturally, as suggested by a 2003 review 4. Staying well-hydrated is also essential for maintaining lip moisture regardless of vitamin status, as highlighted in a 2019 meta-analysis 5.