From the Guidelines
I strongly advise against using "monjaro" once a month for weight loss maintenance due to the lack of information on its efficacy and potential risks associated with incorrect dosing intervals. If you're referring to Mounjaro (tirzepatide), this is an FDA-approved medication for type 2 diabetes that has shown effectiveness for weight management when used weekly, not monthly. Monthly dosing of tirzepatide has not been established as effective for weight loss maintenance. For weight management medications to work properly, they must be taken at their prescribed frequency - typically weekly for medications like tirzepatide, semaglutide (Wegovy), or liraglutide (Saxenda) 1. Using these medications at incorrect intervals would likely result in suboptimal results and potentially increased side effects. Some key points to consider for weight loss maintenance include:
- Long-term comprehensive weight loss maintenance programs that provide at least monthly contact with trained interventionists and focus on ongoing monitoring of body weight and/or other self-monitoring strategies 1
- Participation in high levels of physical activity (200–300 min/week) 1
- Continued focus on nutrition and behavioral changes 1 If you're seeking weight loss maintenance options, I recommend consulting with a healthcare provider who can prescribe an appropriate medication with proven efficacy and proper dosing instructions based on your specific health needs and goals. It's also important to note that there is no clear evidence that nutrition supplements are effective for obesity management or weight loss, and high-quality published studies show little or no weight loss benefits 1. Instead, vitamin/mineral supplementation may be indicated in cases of documented deficiency, and protein supplements may be indicated as adjuncts to medically supervised weight loss therapies 1. Ultimately, the most effective approach to weight loss maintenance will depend on individual circumstances and should be guided by a healthcare professional.
From the Research
Efficacy of Monjaro for Weight Loss Maintenance
- There is no available information on the substance "monjaro" in the provided studies, making it difficult to determine its efficacy for weight loss maintenance.
- The studies focus on the efficacy and safety of approved anti-obesity medications such as orlistat, liraglutide, phentermine/topiramate, naltrexone/bupropion, and lorcaserin 2, 3.
- Research suggests that pharmacotherapy, in combination with lifestyle interventions, can result in significant weight loss and improved cardiometabolism 2, 3.
- Specific studies on orlistat and liraglutide have shown that these medications can lead to weight loss, with liraglutide being more effective in achieving and sustaining weight loss 4, 5.
- However, without information on "monjaro", it is not possible to determine its efficacy for weight loss maintenance, and its use once a month for this purpose cannot be recommended or evaluated based on the available evidence.
Alternative Strategies for Weight Loss Maintenance
- Intermittent fasting has been explored as a potential solution for metabolic disorders, but the current scientific evidence is limited, and it is too early to recommend it as a blanket strategy 6.
- Approved anti-obesity medications, such as orlistat and liraglutide, have been shown to be effective in achieving and sustaining weight loss, but their use should be tailored to individual patients and monitored closely due to potential adverse effects 2, 3, 4, 5.