From the FDA Drug Label
The dosage of Sodium Chloride Oral Solution 23.4% is predicated on the specific requirements of the patient based on clinical and laboratory information. Ages 9 to 50 4 ml (equivalent to 936 mg) Children under 9 years and adults over 50 years Consult a physician
The proper dosage and administration of sodium chloride tablets is not directly addressed in the provided drug label, as it refers to an oral solution. However, for the oral solution, the dosage is 4 ml (equivalent to 936 mg) for individuals aged 9 to 50. For children under 9 years and adults over 50 years, it is recommended to consult a physician 1.
From the Research
The proper dosage and administration of sodium chloride tablets for individuals requiring them is 1-2 tablets (1 gram each) taken orally with a full glass of water, 1-4 times daily as directed by a healthcare provider, with the goal of restoring electrolyte balance and managing conditions involving sodium depletion.
Key Considerations
- Dosing varies based on individual needs, with some patients requiring up to 12 grams daily in divided doses 2.
- These tablets should be taken with meals to reduce stomach irritation and should not be crushed or chewed.
- Patients should maintain adequate fluid intake while taking sodium chloride supplements.
- The purpose of supplementation is to restore electrolyte balance, as sodium is essential for nerve function, muscle contraction, and maintaining proper fluid balance in the body.
Administration and Monitoring
- Patients with severe or acutely symptomatic hyponatremia may require urgent treatment with hypertonic saline administration along with monitoring of sodium levels to avoid overly rapid correction 3.
- For patients with hyponatremic encephalopathy, a 100-ml bolus of 3% sodium chloride (513 mEq/L) administered in repeated doses until symptoms reverse, with the goal of increasing the serum sodium 5-6 mEq/L, is the preferred therapy 4.
- Hourly oral sodium chloride tablets may provide an attractive alternative to intravenous 3% NaCl for selected patients with severe hyponatremia, in conjunction with careful monitoring of the serum sodium concentration 5.
Important Precautions
- Patients should never adjust dosage without medical supervision, as improper sodium levels can lead to serious health complications including high blood pressure or fluid retention.
- The use of oral sodium chloride tablets is a recognized treatment approach for hyponatremia, particularly in patients with refractory idiopathic syndrome of inappropriate anti-diuresis 2.