From the Research
Taking pregnenolone in the morning can potentially improve cognitive function, mood, and energy levels throughout the day, with a recommended dosage of 50 mg, as shown in a study published in 2014 1.
Key Points to Consider
- Pregnenolone is a precursor to many hormones in the body, including cortisol, DHEA, and progesterone, and morning administration may help support the body's natural cortisol rhythm.
- Some users report enhanced mental clarity, reduced anxiety, and improved overall well-being, but effects can vary widely between individuals.
- It's essential to start with a low dose and gradually increase if needed, under medical supervision, as potential side effects may include irritability, headaches, or sleep disturbances if taken too late in the day.
- Pregnenolone can interact with certain medications and may not be suitable for everyone, particularly those with hormone-sensitive conditions, as noted in a study published in 2018 2.
Important Considerations
- A study published in 2016 3 highlights the potential therapeutic uses of pregnenolone, including its role in modulating brain-related functions and its potential as a biomarker for disorders.
- However, it's crucial to consult with a healthcare provider before starting any new supplement regimen, especially if you have existing health conditions or are taking other medications, as emphasized in a study published in 1994 4.
Recommendations
- Start with a low dose of 10-50 mg and gradually increase as needed, under medical supervision.
- Monitor for potential side effects and adjust the dosage or discontinue use if necessary.
- Consult with a healthcare provider before starting pregnenolone, especially if you have existing health conditions or are taking other medications.