From the Research
Cyclobenzaprine has not been clearly established as a cause of priapism, and patients taking this medication should be aware of the symptoms of priapism and seek immediate medical attention if they occur. Priapism, a prolonged and often painful erection lasting more than four hours without sexual stimulation, is not listed among the known side effects of cyclobenzaprine in medical literature or product information 1. Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses or pain sensations sent to the brain, primarily used for short-term relief of muscle spasms associated with acute musculoskeletal conditions. While some medications, particularly certain antidepressants, antipsychotics, and drugs used for erectile dysfunction, have been associated with priapism, cyclobenzaprine belongs to a different class of medications 2.
Some key points to consider:
- Priapism is a medical emergency that can lead to permanent erectile dysfunction if not treated promptly 3
- The absence of documented cases of cyclobenzaprine-induced priapism does not completely rule out the possibility of a rare reaction 4
- Patients taking cyclobenzaprine should be aware of the symptoms of priapism and seek immediate medical attention if they occur 5
- Cyclobenzaprine has been associated with other sexual side effects, such as painful ejaculation, but priapism is not a well-documented side effect of this medication 4
In terms of management, if someone experiences priapism while taking cyclobenzaprine, they should seek immediate medical attention. The current management of ischemic priapism revolves around resolving the acute event, preserving erectile function, and reducing the risk of future recurrences 5. Patients should be evaluated on an individual basis and counseled on the risks and benefits of treatment options.