Dizziness Workup
The workup for dizziness should be driven by clinical phenotyping using a timing-and-triggers approach, NOT routine imaging—most patients with isolated dizziness do not require neuroimaging at all. 1
Clinical Phenotyping Framework
The first critical step is categorizing the dizziness pattern, which determines the entire diagnostic pathway:
1. Brief Episodic Vertigo (Triggered by Head Movement)
- Perform Dix-Hallpike maneuver at bedside to diagnose benign paroxysmal positional vertigo (BPPV) 1, 2
- No imaging is needed if typical nystagmus pattern is present 1
- Consider MRI only if atypical features suggest central paroxysmal positional vertigo (CPPV)—such as negative or atypical Dix-Hallpike with persistent symptoms 1, 2
2. Acute Vestibular Syndrome (AVS): Continuous Vertigo with Nausea, Gait Instability, Nystagmus
This is where stroke risk matters most. The approach differs based on neurologic findings:
WITHOUT Associated Neurologic Deficits:
- Use HINTS examination (Head Impulse, Nystagmus, Test of Skew) if you are specifically trained in its use 2
- Critical caveat: HINTS is inaccurate when performed by untrained clinicians and should NOT be used without proper training 2
- Add finger rub test to further exclude stroke 2
- CT head has <1% diagnostic yield and should not be used 1, 2
- MRI with DWI has only 4% yield in isolated dizziness but is preferred if imaging is needed 1
WITH Associated Neurologic Deficits:
- MRI with DWI becomes much more valuable (12% diagnostic yield vs 4% without deficits) 1
- Use MRI as confirmatory test if HINTS suggests central cause or is equivocal 2
- Look for focal neurologic signs, subtle ocular motor findings, gait imbalance 3
3. Spontaneous Episodic Vestibular Syndrome (Recurrent Episodes)
With Hearing Loss or Tinnitus:
- Consider Menière disease clinically 1
- Imaging generally not required unless atypical features
With Brainstem Neurologic Deficits:
- Search for symptoms/signs of cerebral ischemia 2
- Do not use CT 2
- Use CTA or MRA if concern for vertebrobasilar TIA 2
- Conventional angiography remains gold standard for vertebrobasilar insufficiency confirmation but CTA has nearly 100% sensitivity for vertebral artery dissection 1
4. Chronic Disequilibrium with Ataxia
Cerebellar Pattern:
- MRI brain without contrast is appropriate initial imaging 1
- Add contrast if inflammatory, infectious, or neoplastic cause suspected 1
Sensory/Proprioceptive Pattern:
- MRI cervical and thoracic spine without contrast to evaluate dorsal columns 1
- Look for compressive myelopathy, B12/copper deficiency effects, tabes dorsalis 1
- Add contrast if inflammatory/infectious cause suspected 1
5. Nonspecific Dizziness (No Vertigo, Ataxia, or Neurologic Deficits)
This is the most over-imaged scenario. 1
- Imaging is usually NOT indicated 1
- CT diagnostic yield is <1% 1
- MRI DWI yield is only 4% 1
- Consider systemic causes: dehydration, hypotension, vasovagal reaction, anxiety, autonomic dysfunction 1
- All patients with isolated dizziness who had positive CT findings were already suspected to have central cause on bedside evaluation 1
Key Diagnostic Pitfalls
HINTS misuse: Most emergency physicians lack proper training—using HINTS incorrectly is worse than not using it 2. If untrained, rely on presence of neurologic deficits and gait assessment instead.
Over-reliance on CT: CT misses up to 50% of small brainstem strokes early on 3. If stroke is a concern, proceed directly to MRI with DWI.
Imaging isolated dizziness: The trend toward increased imaging (22% getting CT, 10% getting MRI) has not improved outcomes given the extremely low yield 1
Missing vertebrobasilar TIA: In episodic symptoms with brainstem signs, vascular imaging (CTA/MRA) is essential 2
Essential Bedside Examinations
- Orthostatic vital signs for all patients 4
- Dix-Hallpike maneuver for triggered symptoms 2, 4
- HINTS examination only if properly trained and patient has nystagmus 2
- Gait assessment in patients without nystagmus 2
- Focused neurologic exam for focal deficits 3, 4
Bottom line: Clinical phenotyping determines imaging need—most dizziness requires no imaging at all, and when imaging is needed, MRI with DWI is superior to CT for detecting dangerous causes. 1, 2