What is the name of the scalp gel containing calcipotriene 0.005% and betamethasone dipropionate 0.064%?

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Enstilar® (Xamiol®)

The scalp gel containing calcipotriene 0.005% and betamethasone dipropionate 0.064% is marketed under the brand names Enstilar® in the United States and Xamiol® in other regions 1.

Product Details

This fixed-dose combination product is specifically formulated as a gel for scalp psoriasis treatment, though it's also available in other formulations (ointment, foam, cream) for body psoriasis 2, 3.

Key Characteristics:

  • Active ingredients: Calcipotriene (calcipotriol) 50 μg/g (0.005%) + Betamethasone dipropionate 0.5 mg/g (0.064%)
  • Formulation: Gel specifically developed for scalp application
  • Approved indication: Mild to moderate scalp psoriasis in adults 1

Clinical Evidence:

The gel formulation has demonstrated strong efficacy in clinical practice, with 69-74% of patients achieving clear or almost clear status after 52 weeks of treatment, compared to only 27% with vehicle control (P < .001) 1. The AAD-NPF guidelines provide a Grade A recommendation for its use in scalp psoriasis for 4-12 weeks 1.

Important note: The gel vehicle was specifically engineered for scalp use, offering superior cosmetic acceptability and ease of application compared to ointment formulations, which directly impacts patient adherence 4, 2.

References

4
Research

Effective treatment and improvement of quality of life in patients with scalp psoriasis by topical use of calcipotriol/betamethasone (Xamiol®-gel): results.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2011

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.