Which plexus supplies the dorsal penile nerves targeted in a penile nerve block?

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Last updated: October 3, 2026 • View editorial policy

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Penile Nerve Block Targets the Dorsal Nerve of the Penis

A penile nerve block anesthetizes the dorsal nerve of the penis, which is a terminal branch of the pudendal nerve that travels beneath Buck's fascia along the dorsolateral aspect of the penile shaft.

Anatomical Basis

The dorsal nerve of the penis (DNP) consists of two distinct populations of axons 1, 2:

  • Shaft and urethral innervation: Lateral arcading branches radiate from the dorsal midline toward the ventral surface, providing sensory innervation to the lateral and ventral penile shaft 3
  • Glanular innervation: Axons remain in a constant dorsal midline location along the penile shaft before branching abundantly within the glans 3

Clinical Technique Implications

The block is performed by infiltrating local anesthetic at the base of the penis beneath the pubic symphysis, where the paired dorsal nerves run in a predictable dorsolateral position beneath Buck's fascia. This location is proximal to where the nerve branches extensively.

Expected Anesthetic Coverage

When properly performed, dorsal nerve block produces 1:

  • Complete anesthesia of the dorsal, lateral, and glanular aspects of the penis
  • Incomplete coverage of the ventral surface and frenulum, which receive additional innervation from branches of the perineal nerve

Important Caveats

The ventral penis and frenulum have dual innervation - both from DNP branches and from the perineal nerve 4, 1. This explains why some patients may retain sensation ventrally despite adequate dorsal nerve blockade. The perineal nerve travels along the ventral penis covering the corpus spongiosum and communicates with DNP branches at the junction of the corpora cavernosa and spongiosum 4.

Additionally, communicating branches exist between the cavernous nerves and the dorsal nerve at the penile hilum 5, though this is less clinically relevant for superficial nerve blocks.

References

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.