Synthroid Dosage Strengths After 88 mcg
The next available strength of Synthroid after 88 mcg is 100 mcg. 1
Available Synthroid Strengths
According to the FDA-approved drug label, Synthroid (levothyroxine sodium) is available in the following tablet strengths 1:
- 25 mcg
- 50 mcg
- 75 mcg
- 88 mcg (current dose)
- 100 mcg (next strength up)
- 112 mcg
- 125 mcg
- 150 mcg
- 175 mcg
- 200 mcg
- 300 mcg
Dose Adjustment Considerations
When adjusting levothyroxine doses, incremental changes of 12.5-25 mcg/day are typically made 2. The 88 mcg to 100 mcg transition represents a 12 mcg increase, which falls within the standard adjustment range.
Important Timing for Dose Changes
- Wait 4-8 weeks after any dose adjustment before rechecking TSH levels, as this is the time required for TSH to plateau and reflect the new steady state 2
- Smaller dose adjustments may require 8 weeks or longer before TSH levels stabilize 2
Clinical Context Matters
The decision to increase from 88 mcg to 100 mcg should be guided by:
- Current TSH level (goal is normalization of TSH in primary hypothyroidism) 1
- Clinical symptoms
- Patient age and cardiovascular status
- Body weight changes
Note: In elderly patients or those with cardiac disease, even smaller increments (12.5 mcg) may be preferable to the 12 mcg jump from 88 to 100 mcg, which could be achieved by alternating doses 1.