Differential Diagnosis for Globs of Food and Mucous Getting Caught Up in the Throat

• Single Most Likely Diagnosis
  • Gastroesophageal Reflux Disease (GERD): This condition involves the reflux of stomach acid into the esophagus, which can cause irritation and lead to the sensation of food and mucous getting caught in the throat. The symptoms can be exacerbated by lying down or eating certain foods.
• Other Likely Diagnoses
  • Postnasal Drip: Excess mucous production from the nasal passages can drip down the back of the throat, causing the sensation of globs of mucous. This can be due to allergies, colds, or sinus infections.
  • Dysphagia: Difficulty swallowing can lead to food and liquids being trapped in the throat, causing the sensation of globs. This can be due to various causes such as esophageal stricture, achalasia, or neurological disorders.
  • Laryngopharyngeal Reflux (LPR): Similar to GERD, but the refluxed acid reaches the larynx and pharynx, causing irritation and symptoms.
• Do Not Miss Diagnoses
  • Esophageal Cancer: Although rare, esophageal cancer can cause difficulty swallowing and the sensation of food getting stuck in the throat. It is crucial to rule out this diagnosis, especially in older adults or those with a history of smoking or alcohol use.
  • Foreign Body Aspiration: Accidental inhalation of food or objects can cause obstruction and lead to the sensation of globs in the throat. This is a medical emergency and requires prompt attention.
• Rare Diagnoses
  • Zenker's Diverticulum: A rare condition where a pouch forms in the pharynx, trapping food and causing symptoms.
  • Eosinophilic Esophagitis: A chronic inflammatory condition of the esophagus that can cause difficulty swallowing and food impaction.
  • Cystic Fibrosis: A genetic disorder that can cause excessive mucous production, leading to respiratory and gastrointestinal symptoms, including the sensation of globs in the throat.