What is D'Espine sign?

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Last updated: October 4, 2026 • View editorial policy

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D'Espine Sign

D'Espine sign is not a recognized or established clinical sign in modern medical literature. The term does not appear in any of the provided evidence, including recent guidelines from major medical societies, and is not referenced in contemporary clinical practice.

What You May Be Looking For

Based on the phonetic similarity and clinical context, you might be referring to one of these established signs:

The Spine Sign (Thoracic/Lateral Chest Radiography)

This is a well-documented radiological finding with two distinct applications:

On lateral chest X-rays: The spine sign refers to an interruption or reversal of the normal progressive increase in lucency (darkness) of vertebral bodies from superior to inferior 1, 2. Normally, vertebral bodies appear progressively darker as you move down the spine on lateral views. When this pattern is disrupted, it suggests:

  • Lower lobe pneumonia (particularly left lower lobe)
  • Pleural effusion
  • Consolidation
  • Ground-glass opacity
  • Plate-like atelectasis

The sign has moderate sensitivity (60-70%) but good positive predictive value (91-97%) for detecting lower chest abnormalities 1.

The Thoracic Spine Sign (Ultrasound)

In bedside ultrasound: The thoracic spine sign (also called "extension of the thoracic spine sign") is visualized when pleural fluid allows visualization of thoracic vertebral bodies above the diaphragm 3, 4. Normally, you cannot see the spine above the diaphragm on ultrasound due to air in the lungs.

Diagnostic performance for pleural effusion:

  • Sensitivity: 73.7% (92.9% when excluding trace effusions)
  • Specificity: 92.9%
  • Examination time: approximately 3 minutes 3

This sign is particularly useful in emergency department evaluation of patients with dyspnea and thoracic complaints 4.

Clinical Pitfalls

  • The lateral chest radiograph spine sign can be misleading when absent in patients who actually have pneumonia 2
  • Interreader agreement for the spine sign on lateral radiographs is only moderate (κ = 0.12-0.68) 1
  • The ultrasound spine sign may miss trace pleural effusions but is excellent for clinically significant effusions 3

If you were asking about a different sign entirely, please clarify the clinical context (physical examination finding, imaging sign, specific anatomical location) for more accurate guidance.

References

Research

Value of the "spine sign" on lateral chest views.

The British journal of radiology, 2015

Research

Extension of the Thoracic Spine Sign: A New Sonographic Marker of Pleural Effusion.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2015

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Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.