From the Guidelines
The most effective treatment for poison ivy is immediate washing of the affected area with soap and water to remove the urushiol oil, followed by the application of cool compresses for symptom relief. This approach is supported by the 2024 American Heart Association and American Red Cross guidelines for first aid, which recommend washing the exposed area with soap and water or a commercially available decontamination product as soon as possible after exposure 1. The guidelines also suggest that cool compresses may be considered for relief of local symptoms from exposure to poison ivy, oak, or sumac 1.
Some key points to consider in the treatment of poison ivy include:
- Washing with soap and water can remove up to 100% of poison ivy oils if done immediately after contact, with the effectiveness decreasing over time 1
- Topical corticosteroids, such as hydrocortisone cream, may be used to reduce itching and inflammation, although their effectiveness is uncertain for over-the-counter products 1
- Oatmeal baths may be considered for additional relief of local symptoms 1
- Avoid scratching to prevent infection, and seek medical attention if the rash covers large areas of the body, affects the face or genitals, shows signs of infection, or does not improve after a week.
It is essential to note that the extent and severity of symptoms from poison ivy are proportional to the area and duration of exposure, and approximately 50% to 75% of individuals react to urushiol, the allergic compound in Toxicodendron species 1. Therefore, prompt and proper treatment can significantly impact the morbidity, mortality, and quality of life outcomes for individuals affected by poison ivy.
From the FDA Drug Label
Uses temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: eczema psoriasis poison ivy, oak, sumac insect bites detergents jewelry cosmetics soaps seborrheic dermatitis temporarily relieves external anal and genital itching The treatment for poison ivy includes hydrocortisone (TOP) to temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to poison ivy 2.