From the Research
The MMR vaccine is not a recommended treatment for plantar warts, and instead, treatments such as salicylic acid, cryotherapy, or immunotherapy should be considered. Plantar warts are caused by human papillomavirus (HPV), which is completely different from the viruses targeted by the MMR vaccine 1. For treating large plantar warts, recommended options include over-the-counter salicylic acid preparations (typically 17% concentration, applied daily for several weeks), cryotherapy with liquid nitrogen performed by a healthcare provider (usually requiring multiple treatments 2-3 weeks apart), or prescription treatments like cantharidin, podophyllin, or imiquimod 2, 3, 4.
Some key points to consider when treating plantar warts include:
- The use of salicylic acid, which has been shown to be effective in treating plantar warts 5, 2
- The use of cryotherapy, which has been shown to be effective in treating plantar warts, but may have lower cure rates compared to other treatments 3, 4
- The use of immunotherapy, which has been shown to be effective in treating plantar warts, particularly in cases where other treatments have failed 1, 4
- The importance of persistent treatment, as plantar warts can be stubborn and require treatment over weeks to months 2, 4
It's also important to note that while some case reports have suggested intralesional immunotherapy using other vaccines (like Candida antigen) might help with warts by stimulating immune response, the MMR vaccine is not established for this purpose and should only be used for its intended purpose of preventing measles, mumps, and rubella infections 1.
In terms of specific treatment recommendations, a study published in 2021 found that a topical treatment formulation consisting of cantharidin, podophyllin, and salicylic acid had a high cure rate of 97.82% for plantar warts 4. Another study published in 2022 found that a combination of autologous platelet-rich plasma injection and topical salicylic acid 30% solution was effective in treating multiple resistant plantar warts 5.
Overall, the treatment of plantar warts should be individualized and based on the specific characteristics of the wart, as well as the patient's medical history and preferences. The most effective treatment approach will depend on the specific case, and a healthcare provider should be consulted to determine the best course of treatment.