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Last updated: June 10, 2025View editorial policy

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Differential Diagnosis for Swelling and Redness in Penis with Band of Constrictive Tissue

  • Single most likely diagnosis
    • Peyronie's Disease: This condition is characterized by the formation of fibrous scar tissue, leading to a band of constrictive tissue that can cause swelling, redness, and curvature of the penis. The presence of a band of constrictive tissue behind the glans is a hallmark of this disease.
  • Other Likely diagnoses
    • Paraphimosis: This condition occurs when the foreskin is retracted behind the glans and cannot be returned to its original position, leading to swelling, redness, and constrictive tissue. It is a common condition that can cause the symptoms described.
    • Phimosis: This condition is characterized by a tight foreskin that cannot be retracted over the glans, leading to swelling, redness, and constrictive tissue. It is another possible cause of the symptoms.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Penile Cancer: Although rare, penile cancer can cause swelling, redness, and constrictive tissue. It is essential to rule out this condition, as it can be life-threatening if left untreated.
    • Necrotizing Fasciitis: This is a rare but life-threatening condition that can cause swelling, redness, and tissue necrosis. It requires prompt medical attention to prevent serious complications.
  • Rare diagnoses
    • Dupuytren's Contracture of the Penis: This is a rare condition characterized by the formation of fibrous tissue in the penis, leading to curvature and constrictive tissue.
    • Kaposi's Sarcoma: This is a rare type of cancer that can cause swelling, redness, and constrictive tissue in the penis, particularly in immunocompromised individuals.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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