From the FDA Drug Label
DOSAGE AND ADMINISTRATION Seasonal Allergic Rhinitis Adults and Children 12 Years and OlderThe recommended dose of Fexofenadine Hydrochloride Tablets is 60 mg twice daily, or 180 mg once daily with water. Children 6 to 11 YearsThe recommended dose of Fexofenadine Hydrochloride Tablets is 30 mg twice daily with water. Chronic Idiopathic Urticaria Adults and Children 12 Years and OlderThe recommended dose of Fexofenadine Hydrochloride Tablets is 60 mg twice daily or 180 mg once daily with water. Children 6 to 11 YearsThe recommended dose of Fexofenadine Hydrochloride Tablets is 30 mg twice daily with water.
The recommended dosing of Allegra (fexofenadine) is as follows:
- Adults and Children 12 Years and Older: 60 mg twice daily, or 180 mg once daily with water.
- Children 6 to 11 Years: 30 mg twice daily with water. 1
From the Research
For adults and children 12 years and older, the recommended dose of Allegra (fexofenadine) is 60 mg twice daily or 180 mg once daily, as supported by the most recent study 2. The dosing of Allegra (fexofenadine) varies by age and kidney function.
- For children aged 6-11 years, the recommended dose is 30 mg twice daily.
- For children 2-5 years old, the recommended dose is 30 mg twice daily.
- For children 6 months to less than 2 years, the recommended dose is 15 mg twice daily. It is essential to take Allegra with water, as absorption may be decreased if taken with fruit juices or food, such as grapefruit juice, which can reduce the bioavailability of fexofenadine by approximately 30% 2. For those with decreased kidney function, a reduced dose of 60 mg once daily is recommended, as patients with end-stage renal disease (ESRD) have shown a 63% decline in oral clearance (CL/F) of fexofenadine 2. Allegra works by blocking histamine receptors, reducing allergy symptoms like sneezing, runny nose, itchy eyes, and hives without causing significant drowsiness, and it typically begins working within 1 hour and lasts for 12-24 hours depending on the formulation 3. If symptoms don't improve after 3 days or worsen, it is crucial to consult a healthcare provider. The pharmacokinetics of fexofenadine have been extensively studied, and the drug has been shown to have a linear correlation between increasing doses and proportional elevations in pharmacokinetic parameters such as area under the curve from time 0 to infinity (AUC0-∞) and maximum plasma concentration (Cmax) 2.