What is a good antifungal steroid mix similar to Locacorton (Locacorten) Vioform (clioquinol)?

From the Guidelines

A good antifungal steroid combination similar to Locacorten-Vioform is Nystatin-Triamcinolone cream or ointment. This medication combines triamcinolone (a medium-potency steroid) with nystatin (an antifungal agent) to treat inflammatory skin conditions complicated by fungal infections. The typical regimen involves applying a thin layer to affected areas twice daily for 7-14 days, though treatment should not exceed 2-4 weeks to avoid steroid-related side effects. Another alternative is Clotrimazole-Betamethasone dipropionate, which combines a different antifungal with a medium-potency steroid. These combinations work well because the steroid reduces inflammation and itching while the antifungal component eliminates the fungal infection. They're particularly useful for conditions like seborrheic dermatitis, intertrigo, or fungal-infected eczema. It's essential to discontinue use if the condition worsens or if no improvement is seen after one week, and these medications should be avoided on the face unless specifically directed by a healthcare provider 1.

Some key points to consider when using these antifungal steroid combinations include:

• The importance of not exceeding the recommended treatment duration to minimize the risk of steroid-related side effects
• The need for careful consideration before using these medications on the face
• The potential for these combinations to be effective in treating a range of inflammatory skin conditions complicated by fungal infections
• The importance of monitoring for signs of worsening condition or lack of improvement, and adjusting treatment accordingly.

Overall, Nystatin-Triamcinolone cream or ointment and Clotrimazole-Betamethasone dipropionate are viable options for treating inflammatory skin conditions complicated by fungal infections, and their use should be guided by careful consideration of the individual patient's needs and circumstances.

From the Research

Antifungal Steroid Mixes

To find a good antifungal steroid mix similar to Locacorton (Locacorten) Vioform (clioquinol), we can look at the following options:

• Clotrimazole/betamethasone diproprionate, which is a combination of an antifungal agent and a high-potency topical corticosteroid 2, 3
• Lotrisone, which is another combination antifungal/corticosteroid cream 4
• Mycolog-II, which is also a combination antifungal/corticosteroid cream 4

Considerations for Use

When using these antifungal steroid mixes, it's essential to consider the potential risks and benefits. For example:

• Clotrimazole/betamethasone diproprionate can lead to inadequate clearance or exacerbation of fungal infections, as well as cutaneous atrophy, striae, and other skin maladies 3
• The use of high-potency topical corticosteroids can be a concern, especially in high-risk settings such as sensitive areas (face, axillae, groin or diaper region) 2, 3
• Alternative treatments or referral to dermatologists may be recommended for rashes or other skin conditions 3

Alternative Options

In some cases, alternative options may be available, such as:

• Using an agent with inherent anti-inflammatory properties or a combination antifungal/steroid agent with caution 5
• Simultaneous application of a combination of creams, including an antibacterial agent, an antifungal agent, and an anti-inflammatory steroid 6