From the Research
The recommended dosing for ibuprofen in children is 5-10 mg per kilogram of body weight every 6-8 hours, with a maximum of 40 mg/kg/day. For children 6 months and older, ibuprofen (available as Motrin, Advil, or generic formulations) can be given for fever, pain, or inflammation. Liquid formulations typically come in concentrations of 100 mg/5 mL for infants and 100 mg/5 mL or 200 mg/5 mL for children. It's essential to use the measuring device provided with the medication for accurate dosing. Ibuprofen should be given with food to minimize stomach upset. Parents should not exceed the recommended dose or frequency, as this can lead to side effects including stomach irritation, kidney problems, or rarely, liver issues. Ibuprofen works by inhibiting cyclooxygenase enzymes that produce prostaglandins, which are mediators of pain, fever, and inflammation. For children under 6 months, consult a healthcare provider before administering ibuprofen. If symptoms persist beyond 3 days or worsen, medical attention should be sought.
Some key points to consider when administering ibuprofen to children include:
- Always follow the recommended dosage and frequency to minimize the risk of side effects 1
- Use the measuring device provided with the medication to ensure accurate dosing
- Give ibuprofen with food to reduce the risk of stomach upset
- Monitor for signs of side effects, such as stomach irritation, kidney problems, or liver issues
- Consult a healthcare provider before administering ibuprofen to children under 6 months or if symptoms persist or worsen
It's also important to note that ibuprofen has been shown to be effective in reducing fever and pain in children, with a similar safety profile to acetaminophen 2. However, it's crucial to prioritize the child's safety and well-being by following the recommended dosage and seeking medical attention if necessary.
In terms of the evidence, a systematic review and meta-analysis published in 2020 found that ibuprofen was associated with reduced temperature and less pain in children younger than 2 years, with equivalent safety to acetaminophen 1. This study provides strong evidence for the recommended dosing of ibuprofen in children.