What bottle volumes are available for 100,000 U/mL nystatin oral suspension?

Nystatin 100,000 U/mL Oral Suspension Available Volumes

Nystatin oral suspension at 100,000 units/mL is available in 60 mL (2 fl. oz.), 237 mL (8 fl. oz.), and 480 mL (16 fl. oz.) bottles, as well as 5 mL unit dose cups. 1

Available Bottle Sizes

The FDA-approved formulations come in the following volumes 1:

• 60 mL (2 fl. oz.) - Supplied in individual carton with calibrated dropper (bubblegum flavored)
• 237 mL (8 fl. oz.) - Standard bottle (bubblegum flavored)
• 480 mL (16 fl. oz.) - Larger bottle for extended use (bubblegum flavored)

Unit Dose Options

For institutional or controlled dosing settings 1:

• 5 mL unit dose cups - Available individually or in cases of 50 or 100 cups (cherry flavored)

Clinical Context

The IDSA guidelines recommend nystatin suspension (100,000 U/mL) at 4-6 mL four times daily for 7-14 days as an alternative treatment for mild oropharyngeal candidiasis 2. The 60 mL bottle with calibrated dropper is particularly useful for accurate dosing in this indication 1, while the larger 480 mL bottle 1 may be more appropriate for patients requiring prolonged therapy or chronic suppressive treatment.

Important Considerations

• All formulations must be shaken well before use 1
• The suspension contains 0.5% alcohol by volume 1
• Storage at refrigerated temperatures (5°C) extends stability compared to room temperature storage 3