What is Medroxyprogesterone (MPG)?

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Last updated: February 24, 2025View editorial policy

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From the Guidelines

Medroxyprogesterone (MPG) is a progestin medication that has been associated with weight gain, and its use should be carefully considered in patients, especially those with a history of obesity or weight-related issues 1. When evaluating the use of MPG, it's essential to consider the potential impact on weight and overall health. According to a recent study, MPG has been linked to weight gain, particularly when used in combination with estrogen therapy 1. In contrast, other progestins like levonorgestrel, dydrogesterone, and norethisterone may have different effects on weight, with some being considered weight-neutral 1. Some key points to consider when using MPG include:

  • The potential for weight gain, which may be a concern for patients with obesity or related health issues 1
  • The importance of monitoring weight and adjusting treatment as needed to minimize potential negative effects 1
  • The availability of alternative progestins, such as levonorgestrel, dydrogesterone, and norethisterone, which may have different effects on weight and overall health 1
  • The need for individualized treatment planning, taking into account the patient's specific health needs and medical history 1 In terms of dosage and administration, MPG can be used in various forms, including oral and injectable formulations. The specific dosage and administration schedule will depend on the patient's individual needs and the intended use of the medication. For example, in the context of hormonal replacement therapy, MPG may be used in combination with estrogen therapy, with dosages ranging from 200 mg to 10 mg per day, depending on the specific regimen and patient needs 1. Overall, the use of MPG should be carefully considered in patients, with attention to the potential risks and benefits, as well as alternative treatment options 1.

From the Research

Definition of Medroxyprogesterone (MPG)

There are no research papers provided to assist in answering this question about Medroxyprogesterone (MPG).

Related Information

  • The provided studies focus on various topics such as anti-seizure medications 2, computerized decision support for medication review 3, assessing medication adherence in the elderly 4, factors contributing to medication adherence in patients with chronic conditions 5, and patterns of medication use in the ambulatory adult population of the United States 6.
  • None of these studies mention Medroxyprogesterone (MPG) or provide information about its definition or use.

Key Points

  • The studies provided do not offer any relevant information about Medroxyprogasterone (MPG).
  • To find information about Medroxyprogesterone (MPG), it may be necessary to consult other sources or studies that specifically focus on this topic.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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