Why is glucose used as a home remedy for allergic reactions?

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Last updated: June 11, 2025View editorial policy

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From the Research

Glucose is not recommended as a home remedy for allergic reactions. For mild allergic reactions, over-the-counter antihistamines like diphenhydramine (Benadryl) at a dose of 25-50mg every 4-6 hours or cetirizine (Zyrtec) 10mg once daily are appropriate treatments 1. For severe allergic reactions or anaphylaxis, an epinephrine auto-injector (such as EpiPen or Auvi-Q) should be used immediately, followed by calling emergency services (911) 2, 3, 4, 5.

Key Points to Consider

  • Glucose, which is a simple sugar, has no proven anti-allergic properties and would not address the underlying immune response causing allergic symptoms.
  • Allergic reactions occur when the immune system releases chemicals like histamine in response to allergens, and effective treatments work by blocking these chemicals or reducing the immune response.
  • Using glucose instead of proper medication could delay effective treatment and potentially allow a serious allergic reaction to worsen, which could be dangerous or even life-threatening.
  • The most recent and highest quality study 4 supports the early use of epinephrine and suggests a beneficial effect of antihistamines in the management of anaphylaxis.

Treatment Options

  • For mild allergic reactions:
    • Diphenhydramine (Benadryl) at a dose of 25-50mg every 4-6 hours
    • Cetirizine (Zyrtec) 10mg once daily
  • For severe allergic reactions or anaphylaxis:
    • Epinephrine auto-injector (such as EpiPen or Auvi-Q) immediately
    • Call emergency services (911) immediately after administering epinephrine.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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