From the Guidelines
The determination of Type A versus Type B Chronic Obstructive Pulmonary Disease (COPD) is primarily based on clinical presentation and physiological characteristics, rather than a specific diagnostic test. When determining the type of COPD, several factors are considered, including:
- Clinical presentation, such as symptoms and medical history
- Physiological characteristics, such as lung function and blood oxygen levels
- Presence of concomitant chronic diseases, which can affect mortality and hospitalizations 1 The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report from 2017 emphasizes the importance of assessing the level of airflow limitation, the impact of disease on the patient's health status, and the risk of future events to guide therapy 1. In clinical practice, the distinction between Type A and Type B COPD is not always clear-cut, and most patients have features of both types, making it more of a spectrum than distinct categories. Key characteristics of Type A COPD include severe dyspnea, minimal cough with scant sputum production, and significant hyperinflation of the lungs, while Type B COPD is characterized by chronic productive cough, frequent respiratory infections, and significant hypoxemia leading to cyanosis. Pulmonary function tests, such as spirometry, can help differentiate between the two types, with Type A showing more emphysematous changes and Type B demonstrating more airway obstruction 1.
From the Research
Determination of Type A versus Type B Chronic Obstructive Pulmonary Disease (COPD)
The determination of Type A versus Type B COPD is based on several factors, including:
- The degree of airflow limitation, as measured by the forced expiratory volume in one second (FEV1) and the forced vital capacity (FVC) ratio [(2,3,4)]
- The severity of symptoms, such as dyspnea and cough [(2,5)]
- The presence of comorbidities, such as cardiovascular disease and diabetes 5
- The results of lung function tests, including spirometry and diffusing capacity of the lungs for carbon monoxide (DLco) [(3,4,6)]
Lung Function Tests
Lung function tests are essential for the diagnosis and management of COPD. The most commonly used tests include:
- Spirometry, which measures the FEV1 and FVC [(2,3,4,6)]
- DLco, which measures the ability of the lungs to transfer gas from the air into the bloodstream [(3,4,6)]
- Lung volume measurement, which measures the amount of air in the lungs [(3,4)]
Classification of COPD Severity
The severity of COPD can be classified using several different systems, including:
- The Global Initiative for Chronic Obstructive Lung Disease (GOLD) system, which classifies COPD into four stages based on the FEV1 percentage predicted [(2,4)]
- The STaging of Airflow obstruction by Ratio (STAR) system, which classifies COPD into four stages based on the FEV1/FVC ratio 2