What is the recommended dose and frequency of Methocarbamol (Robaxin)?

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From the FDA Drug Label

DOSAGE AND ADMINISTRATION Methocarbamol, 500 mg — Adults: Initial dosage: 3 tablets q.i.d. Maintenance dosage: 2 tablets q.i.d. Methocarbamol, 750 mg — Adults: Initial dosage: 2 tablets q.i.d. Maintenance dosage: 1 tablet q.4h. or 2 tablets t.i.d. Six grams a day are recommended for the first 48 to 72 hours of treatment. (For severe conditions 8 grams a day may be administered). Thereafter, the dosage can usually be taken to approximately 4 grams a day. The recommended dose and frequency of Methocarbamol (Robaxin) are:

  • Initial dosage:
    • 500 mg: 3 tablets q.i.d. (four times a day)
    • 750 mg: 2 tablets q.i.d. (four times a day)
  • Maintenance dosage:
    • 500 mg: 2 tablets q.i.d. (four times a day)
    • 750 mg: 1 tablet q.4h. (every 4 hours) or 2 tablets t.i.d. (three times a day)
  • Total daily dose:
    • 6 grams per day for the first 48 to 72 hours of treatment
    • Up to 8 grams per day for severe conditions
    • Approximately 4 grams per day thereafter 1

From the Research

The standard adult dose of Robaxin (methocarbamol) is 1500 mg four times daily, or 1000 mg three times daily, with a maximum recommended daily dose of 8000 mg. The typical regimen is to take 1500 mg four times a day for the first 48 to 72 hours, then reduce to 1000 mg four times daily or 750 mg every 4 hours as needed for muscle spasm relief.

  • Robaxin should be taken with food to reduce the risk of stomach upset.
  • This medication is generally prescribed for short-term use, usually 7 to 14 days, as it's intended for acute muscle spasms rather than chronic conditions.
  • Patients should be aware that Robaxin may cause drowsiness and dizziness, so caution is advised when driving or operating machinery.
  • The dosage may be adjusted by a healthcare provider based on individual response and tolerability. Unfortunately, none of the provided studies 2, 3, 4, 5, 6 directly address the dosage and frequency of Methocarbamol (Robaxin), so the answer is based on general medical knowledge and not supported by the given evidence.

References

Research

[Pregabalin--profile of efficacy and tolerability in neuropathic pain].

Drugs of today (Barcelona, Spain : 1998), 2009

Research

The optimal analgesic dose of rofecoxib: Overview of six randomized controlled trials.

Journal of the American Dental Association (1939), 2000

Research

Divalproex sodium in migraine prophylaxis: a dose-controlled study.

Cephalalgia : an international journal of headache, 1997

Research

[Safety of use of micronized diosmin at daily doses up to 2000 mg per day].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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