How are clinical injuries that occur during percutaneous nephrolithotomy (PCNL) managed?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 18, 2026 • View editorial policy

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.

Management of Clinical Injuries During PCNL

For bleeding complications during PCNL, persistent hemorrhage should prompt arteriographic evaluation with transcatheter embolization as the primary treatment, while organ injuries (bowel, liver, pleural) are typically managed conservatively with prolonged drainage and observation in hemodynamically stable patients. 1

Hemorrhagic Complications

Mild Bleeding

  • Clinically asymptomatic hematuria occurs in approximately 50% of patients post-PCNL and requires no specific intervention 1
  • Simple observation is appropriate for self-limiting bleeding

Clinically Significant Bleeding

When persistent bleeding into the collecting system or retroperitoneum occurs:

  1. Immediate arteriographic evaluation to identify:

    • Pseudoaneurysms
    • Arteriovenous fistulas
    • Frank arterial extravasation 1, 2
  2. Transcatheter embolization is the definitive treatment:

    • Success rates of 82-88% for vascular injuries 3
    • Performed as sub-selectively as possible to minimize parenchymal infarction 3
    • Typically uses coils with or without gelfoam 1

Blood transfusion thresholds: The SIR quality improvement guidelines set acceptable transfusion rates at 15% following percutaneous nephrolithotomy 1

Risk factors: Thrombocytopenia increases bleeding risk significantly 1

Organ Injuries

Bowel Perforation (Colon or Small Bowel)

Incidence: 0.3-0.8% of cases, with SIR threshold <1% 1, 4

Management approach (in hemodynamically stable patients without peritonitis):

  • Conservative management is first-line 5, 4, 6:

    • Delay nephrostomy tube removal (average 6.44 days) 5
    • Parenteral nutrition
    • Broad-spectrum antibiotics
    • Serial clinical monitoring
  • Novel endoscopic approach: Colonoscopy with OTSC clip placement at entry/exit points has shown success 6

  • Surgical intervention reserved for:

    • Signs of peritonitis
    • Hemodynamic instability
    • Failed conservative management
    • Options include primary closure or colostomy creation 4, 6

Hepatic Puncture Injury

Management (for hemodynamically stable patients) 5:

  • Conservative treatment with delayed nephrostomy removal (typically 6-7 days)
  • Monitor hemoglobin (average drop: 14.25 g/L)
  • Blood transfusion only if clinically indicated
  • Serial imaging to monitor for subcapsular hematoma

Classification: Tangential vs. penetrating injuries based on 3D-CT reconstruction 5

Splenic and Gallbladder Injuries

  • Rare complications 1, 7
  • Conservative management with observation and drainage typically successful 7
  • Surgical consultation if hemodynamic compromise develops

Pleural Complications

Incidence: 1% for PCN alone, 15% for percutaneous nephrolithotomy 1

Types: Pneumothorax, hemothorax, empyema

Risk factors: Upper-pole calyceal puncture via intercostal approach 1

Management:

  • Small pneumothorax: Observation
  • Symptomatic/large pneumothorax: Chest tube placement
  • Hemothorax/empyema: Drainage with appropriate chest tube

Ureteral Injuries

If ureteral injury occurs during PCNL:

Partial injuries:

  • Ureteral stenting ± diverting nephrostomy 3
  • Observation if stent successfully placed

Complete transection:

  • Percutaneous nephrostomy for urinary diversion 3
  • Delayed surgical repair (primary ureteroureterostomy or reimplantation)
  • Always place double-J stent with any repair to reduce stricture formation 3

Sepsis Management

Incidence: Septic shock in 4% (10% with pyonephrosis) 1

Management:

  • Immediate broad-spectrum antibiotics
  • Hemodynamic support
  • Ensure adequate drainage (nephrostomy tube must remain patent)
  • ICU admission for severe cases

Risk factors: Diabetes and renal calculi (though not definitively predictive) 1

Key Principles

Common pitfall: Attempting to continue the procedure when significant bleeding or organ injury is suspected. Abort the procedure, place nephrostomy tube for drainage, and address the complication definitively before attempting stone removal.

Vascular injury threshold: The SIR guidelines set acceptable rates for vascular injury requiring embolization or nephrectomy at 1% 1

Critical timing: For renal artery injuries, warm ischemia time >60 minutes leads to exponential kidney function loss 3

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.