What is the recommended dose of amoxicillin (amox) for an 11-year-old female weighing 32 kg in pill form?

From the Guidelines

For an 11-year-old female weighing 32 kg, the recommended dose of amoxicillin in pill form is 50 mg per kg once daily, which translates to approximately 1600 mg per day, but the maximum dose is 1000 mg, so the dose should be 1000 mg once daily. The exact dosage depends on the severity of the infection being treated, and the treatment duration is usually 10 days, as recommended by the IDSA guideline for managing group A streptococcal pharyngitis 1.

Key Considerations

• The dose of amoxicillin for children is typically calculated based on their weight, with a recommended dose of 50 mg per kg once daily, not to exceed 1000 mg per day 1.
• The treatment duration for most infections is 10 days, and it's essential to complete the entire prescribed course even if symptoms improve before the medication is finished.
• Amoxicillin works by inhibiting bacterial cell wall synthesis, causing bacterial cell death, and common side effects may include diarrhea, stomach upset, or rash.

Important Notes

• The IDSA guideline provides strong, high-quality evidence for the recommended dose of amoxicillin in children, and it's essential to follow these guidelines to ensure effective treatment and minimize the risk of antibiotic resistance 1.
• Other studies, such as the antimicrobial treatment guidelines for acute bacterial rhinosinusitis, may provide additional guidance on the use of amoxicillin in children, but the IDSA guideline is the most relevant and up-to-date source for this specific question 1.

From the FDA Drug Label

Table 1 ... Weight Less than 40 kg ... Mild/ Moderate 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours Severe 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours

For an 11-year-old female weighing 32 kg, the recommended dose of amoxicillin is:

• Mild/Moderate infections: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours
• Severe infections: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours To calculate the dose:
• 25 mg/kg/day = 25 mg/kg * 32 kg = 800 mg/day, which can be divided into 400 mg every 12 hours or 267 mg every 8 hours (approximately 250-300 mg every 8 hours, as 267 mg is not a standard dose)
• 20 mg/kg/day = 20 mg/kg * 32 kg = 640 mg/day, which can be divided into 320 mg every 12 hours or 213 mg every 8 hours (approximately 200-250 mg every 8 hours, as 213 mg is not a standard dose)
• 45 mg/kg/day = 45 mg/kg * 32 kg = 1440 mg/day, which can be divided into 720 mg every 12 hours or 480 mg every 8 hours
• 40 mg/kg/day = 40 mg/kg * 32 kg = 1280 mg/day, which can be divided into 640 mg every 12 hours or 427 mg every 8 hours (approximately 400-500 mg every 8 hours, as 427 mg is not a standard dose) Given the available pill forms, the dose can be approximated to the nearest available strength. 2

From the Research

Amoxicillin Dosage for an 11-year-old Female

• The recommended dose of amoxicillin for an 11-year-old female weighing 32 kg is not directly stated in the provided studies 3, 4, 5, 6, 7.
• However, study 6 mentions the use of amoxicillin/clavulanate in treating community-acquired infections, but does not provide specific dosage information for an 11-year-old female.
• Study 7 compares the bacteriological efficacies of three macrolides with amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae, but also does not provide specific dosage information for an 11-year-old female.
• Since the provided studies do not offer direct guidance on the dosage of amoxicillin for an 11-year-old female weighing 32 kg, it is essential to consult a healthcare professional or a reliable medical resource for accurate and personalized advice 3, 4, 5, 6, 7.

Considerations for Amoxicillin Dosage

• The dosage of amoxicillin may depend on various factors, including the type and severity of the infection, as well as the patient's weight, age, and medical history.
• It is crucial to follow the recommended dosage and administration guidelines to ensure effective treatment and minimize the risk of adverse effects.
• A healthcare professional can provide personalized guidance on the appropriate dosage and treatment duration for an 11-year-old female weighing 32 kg 3, 4, 5, 6, 7.