How many times can I take a 30 mg tablet of gliclazide (modified‑release) per day?

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Last updated: October 21, 2026 • View editorial policy

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Gliclazide 30 mg: Dosing Frequency

Gliclazide modified-release (MR) 30 mg should be taken once daily, typically before breakfast or the main meal. The maximum recommended dose is 120 mg per day, which means you can take up to four 30 mg tablets, but they should all be taken together as a single daily dose, not split throughout the day 1.

Standard Dosing Guidelines

For gliclazide MR formulations:

  • Once daily administration is the standard approach
  • Take at the same time each day
  • Typically administered before the largest meal (usually breakfast or the evening meal during Ramadan fasting) 1
  • The 30-120 mg dose range is given as a single daily dose, not divided 2, 3

Important Dosing Considerations

Dose titration:

  • Starting dose is typically 30 mg once daily
  • Can be increased to 60 mg, 90 mg, or maximum 120 mg based on glycemic control
  • Adjustments should be made gradually based on blood glucose response 2, 3

Special circumstances:

  • During Ramadan fasting: Switch timing from morning to evening (before the sunset meal/Iftar) but maintain once-daily dosing 1, 4
  • Elderly or those with renal impairment: Start conservatively but still maintain once-daily dosing 5

Critical Safety Point

Do not split the daily dose into multiple administrations. Gliclazide MR is specifically formulated for once-daily dosing to provide 24-hour glycemic control 6, 2. Taking it multiple times per day would defeat the purpose of the modified-release formulation and could increase hypoglycemia risk.

If you need 120 mg total: Take all four 30 mg tablets together once daily, not one tablet four times daily.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.