What is the evidence for using oral collagen supplements to reduce wrinkles?

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Last updated: June 12, 2025View editorial policy

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From the Research

Oral collagen supplements, specifically 2.5-10 grams of hydrolyzed collagen peptides taken daily for 8-12 weeks, may improve skin elasticity and hydration while reducing the appearance of wrinkles, as supported by the most recent and highest quality study 1. The use of oral collagen supplements has gained popularity in recent years, with many studies investigating their potential benefits for skin health.

  • The majority of studies have shown that oral collagen supplements can improve skin elasticity and hydration, reduce the appearance of wrinkles, and increase dermal collagen density 2, 1, 3.
  • However, it is essential to note that the quality of the evidence varies, and more research is needed to fully understand the effects of oral collagen supplements on skin health 4, 5.
  • The most recent study, published in 2025, found that good sleep quality may enhance the benefits of oral collagen supplementation in preventing skin aging, highlighting the importance of considering lifestyle factors in conjunction with supplement use 1.
  • When choosing an oral collagen supplement, it is crucial to select a high-quality product that is derived from a safe source, such as plant-based or bovine collagen, especially for individuals with allergies to fish or shellfish.
  • Overall, while the evidence is promising, it is essential to approach the use of oral collagen supplements with a critical and nuanced perspective, recognizing both the potential benefits and limitations of the current research.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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