From the Research
The standard recommended dose of Daflon (diosmin/hesperidin) for treating varicose veins is 1000 mg (two 500 mg tablets) daily, typically taken as a single dose in the morning with breakfast, with no specific dose titration generally required for this medication, as it is usually started and maintained at this fixed dosage 1.
Key Points to Consider
- Daflon should be taken with food to improve absorption, as it works by improving venous tone, increasing lymphatic drainage, and reducing inflammation in the blood vessels 2.
- The medication strengthens the walls of veins and reduces capillary permeability, which helps alleviate symptoms such as pain, heaviness, and swelling associated with varicose veins 3.
- Treatment duration is typically long-term for chronic venous insufficiency, with clinical improvements often observed within 2-4 weeks of starting therapy 4.
- For acute hemorrhoidal episodes, the dosage may be increased to 3000 mg daily (two tablets three times daily) for the first 4 days, then reduced to 2000 mg daily (two tablets twice daily) for 3 days, before returning to the standard maintenance dose of 1000 mg daily 5.
Mechanism of Action and Benefits
- Daflon 500 mg has been shown to improve venous tone, reduce symptoms of pain, heaviness, and edema in patients with venous reflux, and accelerate venous ulcer healing when used in addition to elastic compression 1, 5.
- The medication has a comprehensive mode of action on the veins, lymphatics, and microcirculation, making it a method of choice for treating varicose veins and chronic venous insufficiency 2, 3.