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Last updated: June 12, 2025View editorial policy

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Differential Diagnosis for Vomiting

  • Single most likely diagnosis:
    • Gastroenteritis: This is often the most common cause of vomiting, typically resulting from a viral or bacterial infection that inflames the stomach and intestines, leading to symptoms like vomiting, diarrhea, and abdominal cramps.
  • Other Likely diagnoses:
    • Food poisoning: Similar to gastroenteritis, food poisoning occurs when food contaminated with bacteria, viruses, or other toxins is consumed, leading to vomiting, diarrhea, and stomach cramps.
    • Motion sickness: This condition occurs when the body receives conflicting signals from the senses, causing symptoms like vomiting, dizziness, and nausea, especially during travel by car, boat, plane, or other vehicles.
    • Pregnancy-related morning sickness: For women, especially during the first trimester of pregnancy, hormonal changes can lead to nausea and vomiting.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Appendicitis: Although less common, appendicitis can present with vomiting, especially if the appendix ruptures, leading to severe abdominal pain and potentially life-threatening complications if not promptly treated.
    • Intestinal obstruction: This is a blockage that prevents normal flow of the products of digestion, which can cause severe vomiting, constipation, and abdominal pain, requiring immediate medical attention.
    • Pancreatitis: Inflammation of the pancreas can cause severe abdominal pain, vomiting, and potentially life-threatening complications if not properly managed.
  • Rare diagnoses:
    • Brain tumors: Although rare, certain brain tumors can increase intracranial pressure, leading to symptoms like vomiting, especially in the morning.
    • Meningitis: An infection of the protective membranes covering the brain and spinal cord, which can cause vomiting, fever, headache, and stiff neck, requiring urgent medical attention.
    • Addison's disease: A rare disorder of the adrenal glands, which can lead to a variety of symptoms including vomiting, due to the deficiency of cortisol and aldosterone hormones.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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