What is the prevalence of hepatitis B (HBsAg-positive) infection among Filipino blood donors?

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Last updated: October 26, 2026 • View editorial policy

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Hepatitis B Prevalence Among Filipino Blood Donors

The prevalence of hepatitis B (HBsAg-positive) infection among Filipino blood donors is 2.87% based on a 5-year retrospective study from Region 3, Philippines (2013-2017). 1

Specific Prevalence Data

The most relevant study examining Filipino blood donors found 1:

  • Overall HBsAg seroprevalence: 2.87% over the 5-year period (2013-2017)
  • This represented the highest proportion among all transfusion-transmissible infections screened
  • The prevalence showed a decreasing trend from 2013 to 2017

High-Risk Donor Characteristics

The study identified specific donor subgroups with elevated hepatitis B rates 1:

  • Age 25-44 years: Highest seroprevalence rate
  • Male donors: Higher rates than females
  • Replacement donors: Higher rates compared to voluntary donors
  • First-time donors: Significantly higher rates than repeat donors

Clinical Context

This 2.87% prevalence is consistent with the Philippines being in an area of high HBV endemicity, as persons born in such regions and their children are recognized as high-risk populations 2. The guideline framework emphasizes that all blood donations must be screened for HBsAg using sensitive FDA-licensed tests (RIA or EIA with sensitivity <0.5 ng/ml) 2.

Important Caveats

  • The 2.87% figure represents detected cases only—a small number of low-level HBsAg carriers may test false-negative despite sensitive screening methods 2
  • Geographic variation exists within the Philippines; the cited study specifically examined Region 3
  • The decreasing trend suggests improving donor selection and screening practices over time

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.