Differential Diagnosis for Dry, Scaly Skin on the Eyelids

Single Most Likely Diagnosis

• Blepharitis: This is an inflammation of the eyelids that can cause dry, scaly skin. It's a common condition often associated with meibomian gland dysfunction, rosacea, or seborrheic dermatitis.

Other Likely Diagnoses

• Seborrheic Dermatitis: A skin condition that can affect oily areas of the body, including the face and eyelids, leading to dry, scaly patches.
• Eczema (Atopic Dermatitis): Can cause dry, scaly skin on the eyelids, especially in individuals with a history of atopic diseases.
• Contact Dermatitis: An allergic or irritant reaction to substances like makeup, makeup removers, or certain chemicals, leading to dryness and scaling on the eyelids.
• Psoriasis: Although less common on the eyelids, psoriasis can cause dry, scaly patches in this area, especially in individuals with a history of the condition.

Do Not Miss Diagnoses

• Basal Cell Carcinoma: Although rare, basal cell carcinoma can present as a dry, scaly patch on the eyelid. Given its potential for local destruction, it's crucial not to miss this diagnosis.
• Squamous Cell Carcinoma: Similar to basal cell carcinoma, squamous cell carcinoma can appear as a dry, scaly lesion and requires prompt diagnosis and treatment.

Rare Diagnoses

• Lichen Planus: A chronic inflammatory condition that can affect the skin, including the eyelids, causing dryness and scaling.
• Discoid Lupus Erythematosus: A chronic skin condition of sores with inflammation and scarring favoring the face, ears, and scalp but can rarely affect the eyelids.
• Sarcoidosis: A disease characterized by the growth of granulomas (inflammatory cells) in any part of the body, including the skin of the eyelids, leading to dry, scaly lesions.