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Differential Diagnosis for Vertical Nystagmus

  • Single most likely diagnosis
    • Benign paroxysmal positional vertigo (BPPV): This condition is a common cause of vertigo and can present with vertical nystagmus, especially when the patient is in a specific head position. It is usually benign and related to the movement of otolith crystals in the inner ear.
  • Other Likely diagnoses
    • Vestibular migraine: This condition can cause a variety of vestibular symptoms, including vertigo and nystagmus. Vertical nystagmus can be seen, especially during acute episodes.
    • Labyrinthitis: Inflammation of the inner ear can cause vertigo, hearing loss, and nystagmus, including vertical nystagmus.
    • Brainstem or cerebellar stroke: Although less common, strokes in these areas can present with vertigo and nystagmus, including vertical components.
  • Do Not Miss diagnoses
    • Wernicke's encephalopathy: This is a serious condition caused by thiamine deficiency, often seen in alcoholics. It can present with nystagmus (including vertical), ophthalmoplegia, and ataxia. Prompt treatment is crucial to prevent long-term damage.
    • Central vertigo due to multiple sclerosis or other demyelinating diseases: These conditions can cause a wide range of neurological symptoms, including vertigo and nystagmus.
    • Posterior fossa tumors: Tumors in the brainstem or cerebellum can cause vertigo, nystagmus, and other neurological symptoms due to compression or invasion of critical structures.
  • Rare diagnoses
    • Congenital nystagmus: Although typically horizontal, some forms can have a vertical component. It's usually identified early in life.
    • Perilymph fistula: An abnormal connection between the inner and middle ear can cause vertigo and nystagmus, including vertical nystagmus, often related to changes in pressure.
    • Chiari malformation: A structural defect in the cerebellum that can cause a variety of symptoms, including vertigo and nystagmus, due to compression of the brainstem and cerebellum.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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