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Differential Diagnosis for a 17-year-old boy with a swollen, tender, and high-riding right testis

  • Single most likely diagnosis
    • Testicular torsion: This condition is characterized by the twisting of the spermatic cord, cutting off the blood supply to the testis. The symptoms described, including a high-riding testis with abnormal transverse lie and loss of cremasteric reflex, are classic for testicular torsion. Prompt diagnosis and treatment are essential to preserve testicular function.
  • Other Likely diagnoses
    • Epididymitis: Inflammation of the epididymis, usually due to bacterial infection, can cause testicular pain, swelling, and tenderness. However, the presence of a high-riding testis and loss of cremasteric reflex makes epididymitis less likely.
    • Testicular trauma: Direct injury to the testis can cause swelling, pain, and tenderness. The history and physical examination would help differentiate trauma from other conditions.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Testicular tumor with torsion: Although rare, a testicular tumor can undergo torsion, presenting with similar symptoms. Missing this diagnosis could delay treatment of the underlying cancer.
    • Appendicular torsion: Torsion of the appendix testis, a small appendage attached to the testis, can mimic testicular torsion. While not life-threatening, it can cause significant pain and should be considered in the differential diagnosis.
  • Rare diagnoses
    • Henoch-Schönlein purpura (HSP): A systemic vasculitis that can cause testicular pain and swelling, although this is a rare manifestation of the disease.
    • Polyarteritis nodosa (PAN): A systemic vasculitis that can affect the testicular arteries, leading to ischemia and pain. However, this is an extremely rare cause of testicular symptoms in a young male.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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