What is the correct nomenclature for documenting a venous blood gas carbon dioxide level?

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Last updated: October 27, 2026 • View editorial policy

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Correct Nomenclature for VBG CO2 Documentation

The correct nomenclature for documenting a venous blood gas carbon dioxide level is PvCO2 (partial pressure of carbon dioxide in venous blood), with specification of whether the sample is from a central or peripheral vein.

Standard Nomenclature Based on Guidelines

According to the ATS/ACCP standardized nomenclature 1:

  • PaCO2 = arterial partial pressure of CO2
  • PvCO2 = venous partial pressure of CO2 (when referring to mixed venous blood from pulmonary artery)
  • PetCO2 = end-tidal CO2

For clinical documentation, you should specify:

  • Central venous PCO2 (from central venous catheter)
  • Peripheral venous PCO2 (from peripheral vein)

Critical Documentation Requirements

When documenting VBG CO2 values, always include:

  • Source location: Central vs. peripheral venous sample
  • Units: mmHg (standard) or kPa
  • Method: Spectrophotometry via blood gas analyzer
  • Timing: Simultaneous with any arterial sample if comparing

Common Pitfalls to Avoid

Do NOT use these terms interchangeably:

  • PaCO2 and PvCO2 are fundamentally different values
  • Central venous PCO2 typically exceeds arterial by ~4 mmHg in normal cardiac output 2
  • Peripheral venous PCO2 is highly variable and should not be used to estimate PaCO2 2, 3

Never document as:

  • "CO2" alone (ambiguous - could mean content, output, or partial pressure)
  • "VCO2" (this specifically means CO2 output/production per minute) 1
  • "Venous CO2" without specifying partial pressure vs. content

Clinical Context Matters

The reliability of venous CO2 measurements depends critically on:

  • Cardiac output status: Central venous values are only reliable predictors when cardiac output is relatively normal 2
  • Peripheral circulation: Peripheral venous values show poor correlation with arterial values (95% prediction interval -10.7 to +2.4 mmHg) 3
  • Metabolic state: In shock states, the venous-arterial CO2 difference (ΔPCO2) >6 mmHg suggests inadequate tissue perfusion 4

For accurate documentation: State "Central venous PCO2 = X mmHg" or "Peripheral venous PCO2 = X mmHg" rather than generic "VBG CO2."

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.